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Home Cultivated food

The safety of cell culture-derived food – ready for scientific evaluation

by Admin
May 10, 2023
in Cultivated food
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The innovative new technologies of cell culture, tissue engineering and precision fermentation are behind potential new foods such as meat obtained from cultured cells or dairy proteins obtained from microorganisms.

omorrow, EFSA kicks off a two-day scientific colloquium to gather views and insights from leading scientific minds, representatives of European, international and national agencies, technology companies and food operators, consumer groups and an array of individuals and other organisations with an interest in this highly topical issue.

food

EFSA’s aim is to ensure we are taking into account all the latest scientific and risk assessment developments in setting standards for evaluating the safety of these new food technologies. We also want to engage with producers and wider society.

As an appetiser to the event, which is being streamed online live, we spoke to experts in this field to illustrate some of the scientific issues involved and the social and economic backdrop.

What are tissue engineering and precision fermentation?

Ramiro Alberio, one of the panellists at the EFSA colloquium, is a professor of developmental biology at the University of Nottingham in the UK.

Prof Alberio said: “Cell and tissue engineering allows the cultivation of cells and tissues separately from an entire organism. For example, starting from only a few cells sourced from a muscle or another organ, these cells can be grown under controlled conditions without the other parts of the organ.

“Cellular engineering is already being used in medicine to regenerate tissues or replace damaged or diseased cells. The technologies are advanced now and could be applied in other areas, such as the agri-food sector.”

The safety of cell culture-derived food – ready for scientific evaluation cell culture derived food shutterstock 2164389931

So-called precision fermentation is a technology that uses microorganisms to produce specific products such as proteins, human-identical milk oligosaccharides, vitamins or fibre.

Prof Alberio said: “Precision fermentation has been in use already for years to produce medicine such as insulin and food enzymes, for example in cheese production. The science behind this technology is constantly evolving, increasing the array of potential food applications.”

Are foods and food ingredients produced with these technologies safe?

It is EFSA’s role to evaluate the safety of novel foods in the EU, including those derived from new technologies such as cell culture and tissue engineering.

Wolfgang Gelbmann is a senior scientific officer at EFSA in the novel foods area and overall rapporteur for the colloquium.

He said: “So far EFSA has not been asked to evaluate any food derived from cultured animal cells, what people might call ‘lab-grown meat’. But we have assessed several novel food ingredients produced through precision fermentation.

The safety of cell culture-derived food – ready for scientific evaluation Cell Culture Top

“We expect to receive novel food applications on cell-culture derived foods in the coming months and years. So, we are keeping pace with the science to stay prepared when such applications arrive.”

Experts from EFSA’s Panel on Nutrition, Novel Foods and Food Allergens (NDA Panel), particularly its Novel Foods Working Group, will carry out these evaluations.

“We are confident,” said Dr Gelbmann, “that the novel foods guidance prepared by our experts together with EFSA’s other applicable cross-cutting guidance documents are fit for this purpose. Indeed, we’ve evaluated over a hundred applications covering a wide diversity of novel foods using these guidelines in recent years. Nevertheless, we routinely review them to keep them up to date with advances in science and technologies.

“We regularly meet with stakeholders on novel foods in scientific events and workshops to discuss technological challenges and safety aspects. The colloquium is an important ingredient in this ongoing dialogue.”

The safety of cell culture-derived food – ready for scientific evaluation raw meat green background

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